- Status:
- Grey
- Decision Date:
- February 2023
Comments
JAPC advises the types of patients who may require an H2RA include:
1. those needing acid suppression who are genuinely allergic or intolerant or contraindicated to all PPIs, which is rare;
2. those needing acid suppression where low magnesium occurs, which is felt as very rare;
3. those who have needed upward titration for reflux symptoms despite high dose PPIs, where addition of H2RA, generally at night time, helps.
4. occasionally there seems to be a small number who claim not to do well on PPI yet symptomatically get better on H2RA.
For all cases, those not responding well to PPIs should be investigated to make sure diagnosis correct.
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