2nd line option for prophylaxis of migraine. (Decision date - September 2021)
1st line off-label option for the treatment of chronic primary pain. Antidepressants can help with quality of life, pain, sleep and psychological distress, even in the absence of a diagnosis of depression. Review the efficacy and side-effects after 4-6 weeks. See Management of Non-malignant Chronic Pain in Primary Care for further details. (Decision date - October 2021)