Regorafenib

BNF:
8.1.5
Status:
Do Not Prescribe (DNP), Red
Decision Date:
March 2015
 

Comments

DO NOT PRESCRIBE (DNP):

  • NICE TA334  - terminated appraisal
  • NICE TA514 - regorafenib for previously treated advanced hepatocellular carcinoma. (Decision date  - April 2018)

RED:

  • NICE TA488 - for previously treated unresectable or  metastatic gastrointestinal stromal tumours. (Decision date - December 2017)
  • NICE TA555 - previously treated advanced hepatocellular carcinoma. (Decision date - February 2019)
  • NICE TA866 - for previously treated metastatic colorectal cancer. (Decision date - March 2023)

Do Not Prescribe (DNP) Drug Classifications

  • 6: Have NICE guidance that recommends they should not be used

Red Drug Classifications

  • 1: Requiring specialist assessment to enable patient selection, initiation and ongoing treating
  • 2: Requiring long term on-going monitoring of efficacy by a specialist and not suitable for shared care
  • 3: Requiring long term on-going monitoring of toxicity by a specialist (either because of difficulty in recognising side effects or high cost of investigations to identify toxicity)

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