BNF:

4.7.2

Status:

Grey

Decision Date:

None

Comments

GREY:^1,2,4 on recommendation of pain clinic if patient is intolerant to both morphine AND oxycodone

MHRA January 2019: Tapentadol may increase seizure risk in patients taking other medicines that lower seizure threshold, for example, antidepressants and antipsychotics. Serotonin syndrome has also been reported when tapentadol is used in combination with serotoninergic antidepressants.

 

 

 

       

 

 

 

 

 

Grey Drug Classifications

• 1: Lack of data on effectiveness compared with standard therapy
• 2: Lack of data on safety compared with standard therapy
• 4: Lack of data on cost-effectiveness compared with standard therapy

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