GREEN: for use in adults
GREEN: 1st line off-label option for the treatment of chronic primary pain. Antidepressants can help with quality of life, pain, sleep and psychological distress, even in the absence of a diagnosis of depression. Review the efficacy and side-effects after 4-6 weeks. See Management of Non-malignant Chronic Pain in Primary Care for further details. (Decision date - Oct 2021).
GREY after consultant/specialist initiation: 2nd line use in children as per NICE. (Decision date - June 2018).