Dupilumab

BNF:
Not listed
Status:
Do Not Prescribe (DNP), Red
Decision Date:
June 2017
 

Comments

RED:

  • NICE TA534: for treating moderate to severe atopic dermatitis.  (Decision date - Sep 2018).
  • Dupiliumab has been awarded an EAMS status for severe atopic dermatitis.
  • NICE TA751: Dupilumab for treating severe asthma with type 2 inflammation.  (Decision date - February 2022).
  • Use in children 6 to 11 years old as add-on maintenance treatment for severe asthma with type 2 inflammation.  (NHSE commissioned.)  (Decision date - October 2022).

DO NOT PRESCRIBE (DNP): 

  • NICE TA648: for treating chronic rhinosinusitis with nasal polyps.  (Terminated appraisal).  (Decision date - October 2020).
  • NICE TA938: for treating eosinophilic oesophagitis in people 12 years and over (terminated appraisal). (Decision date - January 2024)
  • NICE TA955: for treating moderate to severe prurigo nodularis. Not recommended. (Decision date - April 2024)

 

Do Not Prescribe (DNP) Drug Classifications

  • 6: Have NICE guidance that recommends they should not be used

Red Drug Classifications

  • 1: Requiring specialist assessment to enable patient selection, initiation and ongoing treating
  • 2: Requiring long term on-going monitoring of efficacy by a specialist and not suitable for shared care
  • 3: Requiring long term on-going monitoring of toxicity by a specialist (either because of difficulty in recognising side effects or high cost of investigations to identify toxicity)

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