Estradiol/ norethisterone (Elleste Duet, Kliofem, Evorel Conti, Evorel Sequi)

BNF:
Endocrine
Status:
Green
Decision Date:
March 2020
 

Comments

See menopause management guideline

Tablets

Elleste Duet- 1st line sequential (cyclical) combined tablet. Used in perimenopause and during the first year or two after menopause.

Novofem- alternative sequential combined HRT

Kliofem- 1st line continuous combined tablets for post-menopausal women

Kliovance- alternative continuous combined HRT

Transdermal Patches

Evorel sequi- sequential (cyclical) combined transdermal patch. Used in perimenopause and during the first year or two after menopause.

Evorel Conti- continuous combined transdermal patch for post-menopausal women.

Patches are more expensive than oral preparations but may be suitable for patients with high risk of VTE (e.g. those with a BMI over 30 kg/m2). See local menopause management guideline

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Derby and Derbyshire ICB

Derby and Derbyshire ICB

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