Decision Date:
August 2022


RED: Treatment of obesity and the control of hunger associated with genetically confirmed loss-of-function biallelic pro-opiomelanocortin, including PCSK1, deficiency or biallelic leptin receptor deficiency in adults and children aged ≥6 years. (Decision date - December 2021)

RED: HST21 - Setmelanotide for treating obesity caused by LEPR or POMC deficiency (Decision date - August 2022)

Red Drug Classifications

  • 1: Requiring specialist assessment to enable patient selection, initiation and ongoing treating
  • 2: Requiring long term on-going monitoring of efficacy by a specialist and not suitable for shared care
  • 3: Requiring long term on-going monitoring of toxicity by a specialist (either because of difficulty in recognising side effects or high cost of investigations to identify toxicity)
  • 8. NHS England commissioned – to be used in line with NHSE commissioning intentions

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Derby and Derbyshire ICB

Derby and Derbyshire ICB

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