Status:

Red, Green, Green - after consultant/specialist initiation

Decision Date:

October 2020

Comments

Oral capsules (Utrogestan)

GREEN: 

• Progesterone only component of combined HRT. Oral alternative to Mirena IUS.
• 2nd line option for women requiring combined HRT but unsuitable for or intolerant of standard combination preparations.
• Patient group includes women at high risk of VTE (eg migraines, BMI >30 kg/m2, PMH of VTE) in whom transdermal oestrogen is recommended, but in whom Evorel Conti is not tolerated or unsuitable because of the need for variable oestrogen dose.

Vaginal (Utrogestan vaginal capsule/ Cyclogest pessary)

GREEN consultant/specialist initiation: for prevention of miscarriage as per NICE NG126 (off-label). GP may continue until 16 completed weeks of pregnancy. Avoid in patients with peanut allergy. (Decision date - June 2022/ June 2023 Cyclogest) 

RED: for other indications e.g. supplementation of luteal phase during assisted reproductive technology cycles

Cyclogest considered by the BNF as less suitable for prescribing for premenstrual syndrome and post-natal depression, however Derbyshire JAPC acknowledges that there may be indications where this may be appropriate to use. (Decision date- July 2012)

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