High Cost Drugs exc. from tariff

A number of high cost drugs, devices, procedures and products have been excluded from the scope of the national tariff of payment by results . Following the re-organisation of the NHS these drugs are commissioned by:

  • NHS England or
  • the Clinical Commissioning Groups


A detailed list of the NHS National Tariff Payment System for 2020 to 2021 is available here

A summary of PbR excluded from tariff drugs commissioned by CCG or NHSE is available here (2020-21)

A detailed list of medicines directly commissioned by NHS England is available here - (Version 16.1 2020-21)

NHS England are the responsible commissioners for the management of the Cancer Drugs Fund. For details of the CDF click here

A list of technologies with approved Patient Access Schemes is available here


The Manual - this is a technical document describing the prescribed specialised services, some of these are directly commissioned by NHS England and some by CCGs

Commissioning intentions - this serves as notice to all providers of specialised services in England of changes and priorities for the coming year

Gain Sharing - principles for sharing the benefits associated with more efficient use of medicines not reimbursed through national tariff prices


A significant proportion of high cost drugs excluded from tariff are commissioned by Derbyshire in line with NICE Technology Appraisals. Biologic algorithms for use in Dermatology, Gastroenterology, Ophthalmology and Rheumatology are listed below:

Last updated
      Primary hypercholesterolaemia and mixed dyslipidaemia October 2019
      Atopic Dermatitis
March 2021
September 2019
      Crohn's Disease
August 2020
      Ulcerative Colitis
June 2020
      Migraine March 2021
      Sodium oxybate November 2019
      Age-Related Macular Degeneration (ARMD) March 2021
      Diabetic Macular Oedema (DMO) January 2020
      Macular Oedema due to BRVO/CRVO January 2020
      Non-Infectious Posterior Uveitis  September 2019
      Ankylosing Spondylitis July 2019
      Psoriatic Arthritis August 2021
      Moderate Rheumatoid Arthritis August 2021
      Severe Rheumatoid Arthritis April 2021





Derby and Derbyshire CCG

Derby and Derbyshire CCG

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