A number of high cost drugs, devices, procedures and products have been excluded from the scope of the national tariff of payment by results . Following the re-organisation of the NHS these drugs are commissioned by:
NHS National Tariff Payment System for 2025/26 is available here
A summary of PbR excluded from tariff drugs commissioned by ICB or NHSE is available here (2025-26)
A detailed list of medicines directly commissioned by NHS England is available here - (Version 20.0 2025-26)
NHS England are the responsible commissioners for the management of the Cancer Drugs Fund. For details of the CDF (updated April 2025) - click here
A list of technologies with approved Patient Access Schemes is available here
The Manual - this is a technical document describing the prescribed specialised services, some of these are directly commissioned by NHS England and some by ICBs (updated March 2023)
Commissioning intentions - this serves as notice to all providers of specialised services in England of changes and priorities for the coming year
A significant proportion of high cost drugs excluded from tariff are commissioned by Derbyshire in line with NICE Technology Appraisals.
Biologic algorithms for use across Derbyshire are listed below:
| Speciality |
Last updated |
| Cardiology | |
| Primary hypercholesterolaemia and mixed dyslipidaemia | May 2023 |
| Dermatology | |
| Atopic Dermatitis |
September 2025 |
| Psoriasis |
April 2024 |
| Alopecia Areata | July 2024 |
| Generalised Pustular Psoriasis Flares | July 2025 |
| Gastroenterology |
|
| Crohn's Disease |
July 2023 |
| Ulcerative Colitis |
February 2024 |
| ITP | |
| Chronic immune (idiopathic) or refractory chronic thrombocytopenic purpura | April 2023 |
| Neurology | |
| Migraine | November 2023 |
| Sodium oxybate | May 2023 |
| Ophthalmology | |
| Age-Related Macular Degeneration (ARMD) | January 2024 |
| Diabetic Macular Oedema (DMO) | January 2024 |
| Macular Oedema due to BRVO/CRVO | January 2024 |
| Non-Infectious Posterior Uveitis | May 2023 |
| Osteoporosis | |
| Severe Osteoporosis | December 2024 |
| Rheumatology | |
| Ankylosing Spondylitis | November 2023 |
| Psoriatic Arthritis | November 2023 |
| Moderate Rheumatoid Arthritis | August 2025 |
| Severe Rheumatoid Arthritis | August 2025 |