High Cost Drugs exc. from tariff

A number of high cost drugs, devices, procedures and products have been excluded from the scope of the national tariff of payment by results . Following the re-organisation of the NHS these drugs are commissioned by:

  • NHS England or
  • the Integrated Care Board


NHS National Tariff Payment System for 2023 to 2025 is available here

A summary of PbR excluded from tariff drugs commissioned by ICB or NHSE is available here (2024-25)

A detailed list of medicines directly commissioned by NHS England is available here - (Version 19. 2024-25)

NHS England are the responsible commissioners for the management of the Cancer Drugs Fund. For details of the CDF click here

A list of technologies with approved Patient Access Schemes is available here


The Manual - this is a technical document describing the prescribed specialised services, some of these are directly commissioned by NHS England and some by ICBs

Commissioning intentions - this serves as notice to all providers of specialised services in England of changes and priorities for the coming year


A significant proportion of high cost drugs excluded from tariff are commissioned by Derbyshire in line with NICE Technology Appraisals.

Biologic algorithms for use across Derbyshire are listed below:

Last updated
      Primary hypercholesterolaemia and mixed dyslipidaemia May 2023
      Atopic Dermatitis
September 2022
April 2024
      Crohn's Disease
July 2023
      Ulcerative Colitis
February 2024
      Chronic immune (idiopathic) or refractory chronic thrombocytopenic purpura April 2023
      Migraine November 2023
      Sodium oxybate May 2023
      Age-Related Macular Degeneration (ARMD) January 2024
      Diabetic Macular Oedema (DMO) January 2024
      Macular Oedema due to BRVO/CRVO January 2024
      Non-Infectious Posterior Uveitis May 2023
      Romosozumab July 2022
      Ankylosing Spondylitis November 2023
      Psoriatic Arthritis November 2023
      Moderate Rheumatoid Arthritis August 2021
      Severe Rheumatoid Arthritis April 2021





Derby and Derbyshire ICB

Derby and Derbyshire ICB

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